SCHEMBL8516440

SCHEMBL8516440

CCCCCN1CCCOC1=O

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.54
NAAA Q02083 1/20 0.45
ALOX5 P09917 2/20 0.39
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
GBA1 P04062 1/20 0.37
GRM2 Q14416 2/20 0.36
KDM4E B2RXH2 1/20 0.36
PTGS1 P23219 3/20 0.35
PTGS2 P35354 3/20 0.35
MGLL Q99685 3/20 0.35
FAAH O00519 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31308 0.89 NAAA (0.51) PIK3CDNAAAALOX5ALDH1A1GAA
SCHEMBL9250191 0.87 NAAA (0.54) PIK3CDNAAAALOX5ALDH1A1GAA
SCHEMBL27992732 0.87 NAAA (0.54) PIK3CDNAAAALOX5ALDH1A1GAA
SCHEMBL8512828 0.87 NAAA (0.54) PIK3CDNAAAALOX5ALDH1A1GAA
SCHEMBL419534 0.87 NAAA (0.54) PIK3CDNAAAALOX5ALDH1A1GAA
SCHEMBL4860823 0.87 NAAA (0.54) PIK3CDNAAAALOX5ALDH1A1GAA
SCHEMBL14184720 0.87 NAAA (0.54) PIK3CDNAAAALOX5ALDH1A1GAA
Hydrogen Sulfide SCHEMBL28268418 0.87 NAAA (0.50) PIK3CDNAAAALOX5ALDH1A1GAA
SCHEMBL12251950 0.87 PIK3CD (0.59) PIK3CDNAAAALDH1A1GRM2KDM4E
SCHEMBL8150832 0.86 PIK3CD (0.45) PIK3CDNAAAALDH1A1MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0712841-B1 Process for the preparation of 3(N-aryl-amino)-propyl-2'-sulfatoethylsulfonyl compounds DYSTAR TEXTILFARBEN GMBH & CO (DE) 1999-01-13 EP disclosed
EP-0712841-A1 Process for the preparation of 3(N-aryl-amino)-propyl-2'-sulfatoethylsulfonyl compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-05-22 EP disclosed