Sugi Predict

Sugi Predict / Compounds / SCHEMBL8157883

SCHEMBL8157883

SCHEMBL8157883

CCCc1cc(Cc2ccc(Oc3ccc(N)cc3)c(CCC)c2)ccc1Oc1ccc(N)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 3/20 0.42
▸ GAA P10253 1/20 0.40
▸ ALDH1A1 P00352 4/20 0.39
▸ HTR2A P28223 1/20 0.39
▸ SLC6A4 P31645 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ CYP3A4 P08684 2/20 0.38
▸ TSHR P16473 2/20 0.38
▸ TDP1 Q9NUW8 2/20 0.38
▸ PPARG P37231 1/20 0.38
▸ TAAR1 Q96RJ0 2/20 0.38
▸ TAAR5 O14804 1/20 0.38
▸ ADRA1A P35348 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8581645 0.92 CYP19A1 (0.45) CYP19A1ALDH1A1RAB9ATAAR1TAAR5
SCHEMBL8157835 0.91 CYP19A1 (0.40) CYP19A1GAAALDH1A1HTR2ASLC6A4
SCHEMBL8578415 0.91 CYP19A1 (0.42) CYP19A1ALDH1A1HTR2ASLC6A4RAB9A
SCHEMBL2945587 0.88 CYP19A1 (0.44) CYP19A1ALDH1A1HTR2ASLC6A4RAB9A
SCHEMBL8152744 0.88 GAA (0.42) CYP19A1GAAALDH1A1HTR2ASLC6A4
SCHEMBL31457250 0.87 HTR2A (0.49) CYP19A1GAAALDH1A1HTR2ASLC6A4
SCHEMBL8580932 0.85 CYP19A1 (0.42) CYP19A1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL8578479 0.85 ALDH1A1 (0.45) CYP19A1ALDH1A1RAB9ATAAR1TAAR5
SCHEMBL2946734 0.82 SKP2 (0.43) CYP19A1SMN1; SMN2TAAR1TAAR5
SCHEMBL8579609 0.82 CYP19A1 (0.40) CYP19A1HTR2ASLC6A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700532-B1 ALIGNMENT LAYER FOR LIQUID CRYSTALS AVENTIS RES & TECH GMBH & CO (DE) 2000-03-29 — — EP disclosed
EP-0604885-B1 Liquid crystal display device HOECHST AG (DE) 1997-12-10 — — EP disclosed
US-5656340-A Liquid crystal display device HOECHST AKTIENGESELLSCHAFT (DE) 1997-08-12 — — US disclosed
EP-0708149-A1 Alignment layer material for liquid crystal display devices HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-24 — — EP disclosed
EP-0700532-A1 ALIGNMENT LAYER FOR LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1996-03-13 — — EP disclosed
EP-0690334-A2 Liquid crystal display device HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-03 — — EP disclosed
US-5437813-A A thin alignment layer comprising an aromatic polyamide-polysiloxane block homo- or copolymer with different content of polysiloxane to adjust optical pretilt angle HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-01 — — US disclosed
EP-0336536-B1 Organic-solvent soluble polyimide and production thereof HITACHI CHEMICAL CO LTD (JP) 1995-06-28 — — EP disclosed
WO-1994028458-A1 ALIGNMENT LAYER FOR LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-08 — — WO disclosed
EP-0604885-A1 Liquid crystal display device HOECHST AKTIENGESELLSCHAFT (DE) 1994-07-06 — — EP disclosed
US-5037862-A Excellent mechanical stability in printing HITACHI CHEMICAL COMPANY, LTD. (JP) 1991-08-06 — — US disclosed
US-4954612-A ORIENTATION CONTROL FOR LIQUID CRYSTAL DISPLAY HITACHI CHEMICAL CO., LTD. (JP) 1990-09-04 — — US disclosed
EP-0336536-A2 Organic-solvent soluble polyimide and production thereof Hitachi Chemical Co., Ltd. (JP) 1989-10-11 — — EP disclosed
US-4791157-A REACTING TRIMELLITIC ACID WITH AROMATIC DIAMINE WITH ETHER GROUPS HITACHI CHEMICAL CO. (JP) 1988-12-13 — — US disclosed
US-4758875-A Resin encapsulated semiconductor device HITACHI, LTD. (JP) 1988-07-19 — — US disclosed