Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479547 | 0.87 | — | — | |
| Pyridine SCHEMBL15010573 | 0.77 | TSHR (0.35) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL27898466 | 0.76 | PTPRA (0.33) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL27895501 | 0.73 | CYP19A1 (0.36) | TSHR | |
| Pyridine SCHEMBL27297234 | 0.73 | CYP1A2 (0.43) | TDP1 | |
| Pyridine SCHEMBL28476914 | 0.71 | L3MBTL1 (0.38) | TDP1 | |
| Pyridine SCHEMBL28109232 | 0.70 | TSHR (0.32) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL29208216 | 0.70 | TDP1 (0.44) | TDP1 | |
| Allylbenzene SCHEMBL28829822 | 0.70 | MAOB (0.46) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL27261817 | 0.70 | CYP3A4 (0.43) | TSHRNAPRTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594001-B1 | Pyrazolo 4,3-c pyridines, a process for their preparation and their use as serotonin reuptake inhibitors | AVENTIS PHARMA INC (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5428169-A | Antidepressants, treating compulsive disorders, stuttering, trichotillomania | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-06-27 | — | — | US | disclosed |
| US-5380847-A | Reaction of 1-methylpiperidine-4-hydrazine, ketone and titanium isopropoxide to form hydrazone | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0594001-A1 | Pyrazolo 4,3-c pyridines, a process for their preparation and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5296491-A | Pyrazolo[4,3-c]pyridines and their use as serotonin reuptake inhibitors | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-22 | — | — | US | disclosed |
| US-5264576-A | Antiserotonin agents, antidepressants and obsessive-compulsive disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-11-23 | — | — | US | disclosed |