SCHEMBL8158504

SCHEMBL8158504

CC(C(=O)O)C1(C(C)C(=O)O)CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.36
TP53 P04637 1/20 0.35
CYP2C19 P33261 2/20 0.33
TSHR P16473 2/20 0.33
LTA4H P09960 1/20 0.33
NFKB1 P19838 1/20 0.33
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
BLM P54132 1/20 0.31
CACNA2D1 P54289 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FFAR3 O14843 1/20 0.31
PPARA Q07869 1/20 0.30
CETP P11597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1874859 0.78 CYP2C19 (0.36) MMETP53CYP2C19TSHRNFKB1
SCHEMBL11316693 0.78 MME (0.35) MMETP53CYP2C19TSHRNFKB1
SCHEMBL11619428 0.77 TP53 (0.36) TP53CYP2C19TSHRNFKB1FFAR3
SCHEMBL22801268 0.76 MME (0.34) MMETP53CYP2C19TSHRLTA4H
SCHEMBL22597349 0.76 MME (0.34) MMETP53CYP2C19TSHRLTA4H
SCHEMBL24555315 0.76 MME (0.34) MMETP53CYP2C19TSHRLTA4H
SCHEMBL21563503 0.76 MME (0.34) MMETP53CYP2C19TSHRLTA4H
SCHEMBL22672402 0.76 MME (0.34) MMETP53CYP2C19TSHRLTA4H
SCHEMBL25042034 0.76 MME (0.34) MMETP53CYP2C19TSHRLTA4H
SCHEMBL22982826 0.76 MME (0.34) MMETP53CYP2C19TSHRLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6071846-A OLEFIN POLYMERIZATION CATALYST WHICH ALLOWS A POLYOLEFIN TO HAVE HIGH STEREOREGULARITY AND HIGH POLYMERIZATION ACTIVITY; SOLID TITANIUM CATALYST COMPONENT COMPRISES A MAGNESIUM ATOM, TITANIUM ATOM, HALOGEN ATOM AND ELECTRON DONOR TOKUYAMA CORPORATION (JP) 2000-06-06 US disclosed
EP-0739907-B1 An olefin polymerization catalyst and a polyolefin production method TOKUYAMA CORP (JP) 1999-12-01 EP disclosed
EP-0739907-A1 An olefin polymerization catalyst and a polyolefin production method TOKUYAMA CORPORATION (JP) 1996-10-30 EP disclosed