Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330916 | 0.93 | TSHR (0.38) | MMETP53CYP2C19TSHRNFKB1 | |
| SCHEMBL28003648 | 0.79 | OPRM1 (0.34) | MMETP53CYP2C19TSHRNFKB1 | |
| SCHEMBL18052040 | 0.79 | EPHX1 (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL17077871 | 0.79 | TP53 (0.32) | TP53 | |
| SCHEMBL8158504 | 0.78 | MME (0.36) | MMETP53CYP2C19TSHRNFKB1 | |
| SCHEMBL11082258 | 0.77 | CYP1A2 (0.36) | TP53CYP1A2 | |
| SCHEMBL1874859 | 0.76 | CYP2C19 (0.36) | MMETP53CYP2C19TSHRNFKB1 | |
| SCHEMBL22140322 | 0.76 | MEN1 (0.34) | CHRM2CHRM1CHRM3LMNASMN1; SMN2 | |
| SCHEMBL22140324 | 0.76 | MEN1 (0.34) | CHRM2CHRM1CHRM3LMNASMN1; SMN2 | |
| SCHEMBL25042034 | 0.74 | MME (0.34) | MMETP53CYP2C19TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2442809-B1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2016-08-31 | — | — | EP | disclosed |
| US-20160152614-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED | 2016-06-02 | — | — | US | disclosed |
| US-20140296201-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED | 2014-10-02 | — | — | US | disclosed |
| US-20140142119-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-05-22 | — | — | US | disclosed |
| EP-0029052-A1 | A PROCESS AND A MEANS FOR CLEANING | TEPAB TEKNISK PRODUKTUTVECKLING AB (SE) | 1981-05-27 | — | — | EP | disclosed |
| WO-1980002693-A1 | A PROCESS AND A MEANS FOR CLEANING | TEPAB TEKNISK PRODUKTUTVEKKLIN (SE) | 1980-12-11 | — | — | WO | disclosed |
| US-4218341-A | COMPLEXING, PRECIPITATION, OR CHEMICAL REDUCTION | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296201-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | ACE, IRF3, ACE2 | MME 41/4885TP53 825/4885CYP2C19 513/4885 |
| US-20160152614-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | ACE, IRF3, ACE2 | MME 41/4885TP53 825/4885CYP2C19 513/4885 |
| US-20140142119-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | ACE, IRF3, ACE2 | MME 41/4885TP53 825/4885CYP2C19 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.