Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44664 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRRAB9ASMN1; SMN2CYP2C19 | |
| SCHEMBL11767820 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C19CYP1A2GAA | |
| SCHEMBL7718086 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TSHRRAB9ACYP2C19CYP1A2 | |
| SCHEMBL10432560 | 0.76 | — | — | |
| SCHEMBL3478608 | 0.76 | CYP3A4 (0.40) | ALDH1A1TSHRCYP1A2CYP2C9SLC22A2 | |
| SCHEMBL7718084 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TSHRRAB9ACYP2C19CYP1A2 | |
| SCHEMBL8517746 | 0.75 | ALDH1A1 (0.39) | ALDH1A1RAB9ACYP2D6MIFHTR3E | |
| SCHEMBL8083518 | 0.72 | MIF (0.40) | ALDH1A1TSHRRAB9ACYP2C19CYP1A2 | |
| SCHEMBL10443511 | 0.70 | ALDH1A1 (0.35) | ALDH1A1MIF | |
| SCHEMBL7775723 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRSMN1; SMN2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | claimed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | claimed |
| EP-0315367-B1 | Polypeptides | ICI PLC (GB) | 1994-04-06 | — | — | EP | claimed |
| US-5081107-A | Bombesin or bombesin-like peptides antagonists; anticarcinogenic agents; antisecretory agents; glandular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | claimed |
| US-5068222-A | Polypeptides for treatment of cancer | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-26 | — | — | US | claimed |
| EP-0345990-A2 | Polypeptide compounds | ZENECA LIMITED (GB) | 1989-12-13 | — | — | EP | claimed |
| EP-0315367-A2 | Polypeptides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-10 | — | — | EP | claimed |
| JP-1151599-A | — | — | None | — | — | JP | disclosed |
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | disclosed |
| EP-0315367-B1 | Polypeptides | ICI PLC (GB) | 1994-04-06 | — | — | EP | disclosed |
| US-5081107-A | Bombesin or bombesin-like peptides antagonists; anticarcinogenic agents; antisecretory agents; glandular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| US-5068222-A | Polypeptides for treatment of cancer | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-26 | — | — | US | disclosed |
| EP-0345990-A2 | Polypeptide compounds | ZENECA LIMITED (GB) | 1989-12-13 | — | — | EP | disclosed |
| JP-H01151599-A | POLYPEPTIDE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITION USED IN TREATMENT OF DISEASES OR MEDICAL CONDITION ARRANGED BY BOMBESIN OR BOMBESIN-LIKE PEPTIDE | IMPERIAL CHEM IND PLC <ICI> | 1989-06-14 | — | — | JP | disclosed |
| EP-0315367-A2 | Polypeptides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-10 | — | — | EP | disclosed |