Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 1.00 |
| ▸ | F9 | P00740 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169809 | 0.89 | F10 (1.00) | F10F2KLK1 | |
| SCHEMBL8166353 | 0.88 | F10 (0.79) | F10 | |
| SCHEMBL8165043 | 0.85 | F10 (1.00) | F10F9F2 | |
| SCHEMBL8166448 | 0.85 | F10 (0.74) | F10F2 | |
| SCHEMBL8170384 | 0.85 | F10 (1.00) | F10F9F2 | |
| SCHEMBL8166126 | 0.83 | F10 (1.00) | F10 | |
| SCHEMBL8166226 | 0.80 | F10 (1.00) | F10F2 | |
| SCHEMBL8165749 | 0.80 | F10 (0.84) | F10 | |
| SCHEMBL8166444 | 0.79 | F10 (1.00) | F10F2KLK1 | |
| SCHEMBL8158646 | 0.75 | F10 (0.80) | F10F9F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |