SCHEMBL8166126

SCHEMBL8166126

CN(C)C(=N)c1ccc(NC(=O)c2cc(C(F)(F)F)nn2-c2cc3ccccc3cc2F)c(F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8163632 0.89 F10 (0.80) F10
SCHEMBL8165451 0.88 F10 (1.00) F10
SCHEMBL8169288 0.86 F10 (0.75) F10
SCHEMBL8165515 0.84 F10 (1.00) F10
SCHEMBL8166139 0.83 F10 (1.00) F10
SCHEMBL8158680 0.83 F10 (1.00) F10
SCHEMBL8158088 0.80 F10 (0.85) F10
SCHEMBL8170664 0.79 F10 (1.00) F10
SCHEMBL8168539 0.78 F10 (1.00) F10
SCHEMBL8404439 0.78 F10 (0.68) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed
US-20040116399-A1 Inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. 2004-06-17 US disclosed