Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 15/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381938 | 1.00 | MRGPRX4 (0.63) | MRGPRX4 | |
| SCHEMBL8158936 | 1.00 | MRGPRX4 (0.63) | MRGPRX4 | |
| SCHEMBL29740791 | 0.91 | MRGPRX4 (0.62) | MRGPRX4 | |
| SCHEMBL16743013 | 0.91 | MRGPRX4 (0.62) | MRGPRX4 | |
| SCHEMBL8165185 | 0.91 | MRGPRX4 (0.51) | MRGPRX4 | |
| SCHEMBL8165193 | 0.91 | MRGPRX4 (0.51) | MRGPRX4 | |
| SCHEMBL17200662 | 0.90 | MRGPRX4 (0.60) | MRGPRX4 | |
| SCHEMBL8158229 | 0.85 | MRGPRX4 (0.50) | MRGPRX4 | |
| SCHEMBL8158236 | 0.85 | MRGPRX4 (0.50) | MRGPRX4 | |
| SCHEMBL7170044 | 0.84 | HTT (0.60) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084120-A | ACTIVE AGAINST CHLOROQUINE-SENSITIVE PATIENTS AND AGAINST CHLOROQUINE-RESISTANT MALARIA PATHOGENS; PROPHYLAXIS AND TREATMENT; E.G., A 3 METHOXY-2-(2-(4-PHENYLBUTA-1,3-DIEN-1-YL)PHENYL)ACRYLIC ACID | HOFFMANN-LA ROCHE INC. (US) | 2000-07-04 | — | — | US | disclosed |