SCHEMBL8158936

SCHEMBL8158936

CO/C=C(/C(=O)OC)c1ccccc1COc1ccc(C(F)(F)F)cc1Cl

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 15/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381938 1.00 MRGPRX4 (0.63) MRGPRX4
SCHEMBL8158938 1.00 MRGPRX4 (0.63) MRGPRX4
SCHEMBL29740791 0.91 MRGPRX4 (0.62) MRGPRX4
SCHEMBL16743013 0.91 MRGPRX4 (0.62) MRGPRX4
SCHEMBL8165185 0.91 MRGPRX4 (0.51) MRGPRX4
SCHEMBL8165193 0.91 MRGPRX4 (0.51) MRGPRX4
SCHEMBL17200662 0.90 MRGPRX4 (0.60) MRGPRX4
SCHEMBL8158229 0.85 MRGPRX4 (0.50) MRGPRX4
SCHEMBL8158236 0.85 MRGPRX4 (0.50) MRGPRX4
SCHEMBL7170044 0.84 HTT (0.60) MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121586714-A Connected bicyclic compounds for control and combating invertebrate pests FMC公司 2026-02-27 CN claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
CN-114222498-A Material delivery system and method FMC公司 2022-03-22 CN claimed
WO-2026101910-A1 FUNGICIDAL FORMULATIONS CONTAINING ARYL AMIDINES AND METHODS OF USE CORTEVA AGRISCIENCE LLC (US) 2026-05-15 WO disclosed
CN-121586714-A Connected bicyclic compounds for control and combating invertebrate pests FMC公司 2026-02-27 CN disclosed
EP-4666856-A2 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2025-12-24 EP disclosed
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-12-09 US disclosed
US-20250368612-A1 MOLECULE HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-12-04 US disclosed
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-27 US disclosed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP disclosed
EP-3040073-A1 APPLICATIONS OF SUBSTITUENT BENZYLOXY GROUP CONTAINING ETHER COMPOUNDS FOR PREPARING ANTITUMOR DRUGS Sinochem Corporation (CN) 2016-07-06 EP disclosed
US-7947734-B2 have good insecticidal activity; good activity against many pests, especially for Carmine spider mite; plants caused by oomycete, basidiomycete, ascomycete pathogens and deuteromycete; low dosage, high activity; fungicides SINOCHEM CORPORATION (CN) 2011-05-24 US disclosed
US-7947734-B2 have good insecticidal activity; good activity against many pests, especially for Carmine spider mite; plants caused by oomycete, basidiomycete, ascomycete pathogens and deuteromycete; low dosage, high activity; fungicides SINOCHEM CORPORATION (CN) 2011-05-24 US disclosed
US-20080188468-A1 Substituted Para-Trifluoromethyl Phenylate Compounds And Its Preparation And Use Thereof SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) 2008-08-07 US disclosed
US-20080188468-A1 Substituted Para-Trifluoromethyl Phenylate Compounds And Its Preparation And Use Thereof SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) 2008-08-07 US disclosed
EP-1897866-A1 SUBSTITUTED P-TRIFLUOROMETHYL PHENYLETHERS, THE PREPARATIO AND THE USE THEREOF Shenyang Research Institute of Chemical Industry (CN) 2008-03-12 EP disclosed
US-6084120-A ACTIVE AGAINST CHLOROQUINE-SENSITIVE PATIENTS AND AGAINST CHLOROQUINE-RESISTANT MALARIA PATHOGENS; PROPHYLAXIS AND TREATMENT; E.G., A 3 METHOXY-2-(2-(4-PHENYLBUTA-1,3-DIEN-1-YL)PHENYL)ACRYLIC ACID HOFFMANN-LA ROCHE INC. (US) 2000-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080188468-A1 Substituted Para-Trifluoromethyl Phenylate Compounds And Its Preparation And Use Thereof TYR, DDT, TH MRGPRX4 2046/4885
US-20250368612-A1 MOLECULE HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, PLA2G2D, MYO1G MRGPRX4 80/4885
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD MRGPRX4 366/4885
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD MRGPRX4 366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.