SCHEMBL815911

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3047027	0.85	CYP3A4 (0.56)	CYP3A4HPGDALOX5PTGS1PTGS2
	SCHEMBL7195739	0.80	ABL1 (0.50)	CYP3A4ALOX5PTGS2TTRALDH1A1
	SCHEMBL10106588	0.79	CYP3A4 (0.62)	CYP3A4HPGDALOX5PTGS1PTGS2
	SCHEMBL11581623	0.77	ABL1 (0.52)	CYP3A4HPGDALOX5PTGS1PTGS2
	SCHEMBL26093189	0.76	CYP3A4 (0.58)	CYP3A4HPGDPTGS1PTGS2ALDH1A1
	SCHEMBL22119888	0.76	CYP3A4 (0.46)	CYP3A4HPGDALOX5PTGS1PTGS2
	SCHEMBL282134	0.75	ALDH1A1 (0.53)	CYP3A4HPGDALDH1A1CA1CA2
	SCHEMBL15894600	0.74	CYP3A4 (0.45)	CYP3A4HPGDALOX5PTGS1PTGS2
	SCHEMBL16639593	0.74	PTPN1 (0.59)	CYP3A4HPGDALOX5PTGS1PTGS2
	SCHEMBL19360285	0.74	PTPN1 (0.59)	CYP3A4HPGDALOX5PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.