Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.61 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170491 | 0.92 | F10 (0.60) | F10 | |
| SCHEMBL8159660 | 0.88 | F10 (0.79) | F10 | |
| SCHEMBL8405134 | 0.86 | F10 (0.64) | F10KCNH2 | |
| SCHEMBL8166003 | 0.86 | F10 (0.60) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8167211 | 0.86 | F10 (0.62) | F10KCNH2 | |
| SCHEMBL8163847 | 0.86 | F10 (0.78) | F10KCNH2 | |
| SCHEMBL8165979 | 0.85 | F10 (0.63) | F10KCNH2 | |
| SCHEMBL8159612 | 0.81 | F10 (0.47) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8164435 | 0.81 | F10 (0.68) | F10 | |
| SCHEMBL8159618 | 0.80 | F10 (0.46) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |