Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594860 | 0.88 | KDM4E (0.57) | KDM4EGAALMNACYP1A2POLB | |
| SCHEMBL8160677 | 0.82 | KDM4E (0.48) | KDM4EGAALMNACYP1A2POLB | |
| SCHEMBL3115391 | 0.81 | KDM4E (0.52) | KDM4EGAALMNACYP1A2POLB | |
| SCHEMBL8146536 | 0.79 | KDM4E (0.42) | KDM4EGAALMNACYP1A2POLB | |
| SCHEMBL3431093 | 0.77 | KDM4E (0.48) | KDM4EGAALMNACYP1A2POLB | |
| SCHEMBL24535397 | 0.77 | KDM4E (0.40) | KDM4EGAACYP1A2ALDH1A1 | |
| SCHEMBL9443662 | 0.77 | KDM4E (0.53) | KDM4EGAALMNACYP1A2POLB | |
| SCHEMBL10343487 | 0.76 | KDM4E (0.47) | KDM4EGAALMNACYP1A2POLB | |
| SCHEMBL10343301 | 0.76 | KDM4E (0.47) | KDM4EGAALMNACYP1A2POLB | |
| SCHEMBL10383767 | 0.76 | KDM4E (0.47) | KDM4EGAALMNACYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696474-B1 | Catalytic systems and methods for carbonylation | DAICEL CHEM (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0948999-A1 | Catalytic systems and method for carbonylation | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5869738-A | OF AN OLEFIN WITH CARBON MONOXIDE PRODUCING AN ACID | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| US-5731255-A | GROUP VIII METAL SOURCE, LIGAND, ACID | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0696474-A2 | Catalytic systems and methods for carbonylation | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |