Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094157 | 0.83 | CTSS (0.62) | CTSSCD74 | |
| SCHEMBL4572754 | 0.81 | CTSS (0.60) | CTSSCD74 | |
| SCHEMBL4572786 | 0.80 | CTSS (0.76) | CTSS | |
| SCHEMBL4084584 | 0.80 | CTSS (0.77) | CTSS | |
| SCHEMBL4574190 | 0.78 | CTSS (0.60) | CTSS | |
| SCHEMBL4090660 | 0.75 | CTSS (0.59) | CTSS | |
| SCHEMBL8164393 | 0.75 | CTSS (0.59) | CTSS | |
| SCHEMBL14510808 | 0.75 | CTSS (0.84) | CTSSCD74 | |
| SCHEMBL4094442 | 0.75 | CTSS (0.58) | CTSS | |
| SCHEMBL4084795 | 0.74 | CTSS (0.58) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100635-A1 | 1- [3- (MONOCYCLIC AMINO) PROPYL] - 4, 5, 6, 7-TETRAHYDRO-1H-PYRAZOLO [4, 3-C] -PYRIDINES AS MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | disclosed |