Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437 | 0.81 | HTT (0.55) | KMT2AMEN1NPC1S1PR4RAB9A | |
| SCHEMBL8789338 | 0.81 | KMT2A (0.54) | KMT2AMEN1NPC1S1PR4RAB9A | |
| SCHEMBL22583487 | 0.80 | ALDH1A1 (0.50) | KMT2AMEN1NPC1S1PR4RAB9A | |
| SCHEMBL5143899 | 0.79 | NPC1 (0.63) | KMT2AMEN1NPC1S1PR4RAB9A | |
| SCHEMBL4555887 | 0.79 | NPC1 (0.59) | KMT2AMEN1NPC1S1PR4RAB9A | |
| SCHEMBL8565240 | 0.79 | KMT2A (0.51) | KMT2AMEN1NPC1S1PR4RAB9A | |
| SCHEMBL8563924 | 0.77 | KMT2A (0.50) | KMT2AMEN1NPC1S1PR4RAB9A | |
| SCHEMBL15616449 | 0.77 | KMT2A (0.50) | KMT2AMEN1NPC1S1PR4RAB9A | |
| SCHEMBL15767908 | 0.77 | KMT2A (0.50) | KMT2AMEN1NPC1S1PR4RAB9A | |
| SCHEMBL26481653 | 0.77 | NPC1 (0.51) | KMT2AMEN1NPC1S1PR4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154905-A2 | MODIFICATIONS OF THE HISTONE DEACETYLASE INHIBITOR SUBEROYLANILIDE HYDROXAMIC ACID | SCHEBO BIOTECH AG (DE) | 2008-12-24 | — | — | WO | disclosed |