Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 9/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30524328 | 1.00 | EPAS1 (0.36) | EPAS1KIF11CYP11B1CYP11B2P2RX7 | |
| SCHEMBL9392558 | 0.83 | EPAS1 (0.40) | EPAS1KIF11CYP11B1CYP11B2P2RX7 | |
| SCHEMBL11326568 | 0.82 | AR (0.33) | TNFRIPK1 | |
| SCHEMBL8160044 | 0.81 | CYP3A4 (0.43) | TNFRIPK1HTR2AHTR2CHTR2B | |
| SCHEMBL3336349 | 0.81 | NOTUM (0.39) | EPAS1P2RX7PDE2AHTR2AHTR2C | |
| SCHEMBL9035509 | 0.81 | EPAS1 (0.39) | EPAS1KIF11CYP11B1CYP11B2P2RX7 | |
| SCHEMBL14200100 | 0.79 | TNF (0.32) | TNFRIPK1 | |
| SCHEMBL10696453 | 0.77 | CSNK2A2 (0.44) | KIF11P2RX7PDE2A | |
| SCHEMBL10974687 | 0.77 | EPAS1 (0.37) | EPAS1CYP11B1CYP11B2P2RX7PDE2A | |
| SCHEMBL31561613 | 0.77 | CSNK2A2 (0.44) | KIF11P2RX7PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885415-A | HYDROGENATION, DECHLORINATION, CATALYSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-05 | — | — | US | claimed |
| CN-116693363-A | Preparation method of herbicide intermediate | 帕潘纳(北京)科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| US-6114590-A | Process for the preparation of polyhalogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides and new trihalogenobenzotrichlorides and -benzoyl chlorides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |
| US-6075165-A | Process for the preparation of polyhalogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides and new trihalogenobenzotrichlorides and -benzoyl chlorides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
| EP-0607824-B1 | Method for the production of multiply halogenated benzotrichlorides and benzoyl chlorides as well as new multiply halogenated benzotrichlorides | BAYER AG (DE) | 1998-04-22 | — | — | EP | disclosed |
| US-5599980-A | Process for the preparation of polyhalogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides and new trihalogenobenzotrichlorides and -benzoyl chlorides | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |
| EP-0607824-A2 | Method for the production of multiply halogenated benzotrifluorides, benzotrichlorides and benzoyl chlorides as well as trihalobenzotrichlorides and -benzoyl chlorides | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |
| EP-0607825-A1 | 6-H-4-OXO-3-quinoline-carboxylic acids and their analogues as antibacterial agents | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |
| EP-0270964-B1 | PROCESS FOR OBTAINING SUBSTITUTED FLUOROBENZENES | BAYER AG (DE) | 1992-07-08 | — | — | EP | disclosed |
| EP-0302326-B1 | PROCESS FOR PREPARING FLUORINATED AND OPTIONALLY ALSO CHLORINATED BENZOTRIFLUORIDES, AND BENZOTRIFLUORIDES | BAYER AG (DE) | 1992-04-15 | — | — | EP | disclosed |
| US-4962246-A | INSECTICIDE INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | disclosed |
| US-4885415-A | HYDROGENATION, DECHLORINATION, CATALYSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-05 | — | — | US | disclosed |
| US-4868347-A | SOLVENT EXTRACTION | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |
| EP-0302326-A1 | Process for preparing fluorinated and optionally also chlorinated benzotrifluorides, and benzotrifluorides | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |
| US-4424396-A | ARYL HALIDE, A-AMINOACID | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |