Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152361 | 1.00 | PREP (0.64) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL6285952 | 0.86 | PREP (0.65) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL6285958 | 0.86 | PREP (0.65) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10517406 | 0.86 | PREP (0.63) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10517399 | 0.86 | PREP (0.63) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10339417 | 0.84 | PREP (0.65) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL5741647 | 0.84 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7330019 | 0.84 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5741652 | 0.84 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7302071 | 0.83 | PREP (0.62) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017929-A | Cholinesterase activator | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0754454-A1 | CHOLINESTERASE ACTIVATOR | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |