Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285952 | 1.00 | PREP (0.65) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL10339417 | 0.97 | PREP (0.65) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL9501704 | 0.88 | PREP (0.53) | PREP | |
| SCHEMBL5741652 | 0.87 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7330019 | 0.87 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5741647 | 0.87 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8152361 | 0.86 | PREP (0.64) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8159989 | 0.86 | PREP (0.64) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8153245 | 0.84 | MEN1 (0.55) | PREPMEN1NPC1RAB9AKMT2A | |
| SCHEMBL8153242 | 0.84 | MEN1 (0.55) | PREPMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900238-B1 | HIV protease inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-05-31 | — | — | US | disclosed |
| EP-0873519-A4 | HIV PROTEASE INHIBITORS | SCRIPPS RESEARCH INST (US) | 2005-04-27 | — | — | EP | disclosed |
| EP-0873519-A1 | HIV PROTEASE INHIBITORS | The Scripps Research Institute (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997021100-A9 | HIV PROTEASE INHIBITORS | — | 1997-10-30 | — | — | WO | disclosed |
| WO-1997021100-A1 | HIV PROTEASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-06-12 | — | — | WO | disclosed |