Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 18/20 | 0.67 |
| ▸ | EGFR | P00533 | 16/20 | 0.67 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157768 | 0.90 | EGFR (0.71) | FLT1EGFRPRKCQPRKCD | |
| SCHEMBL7115414 | 0.88 | FLT1 (0.69) | FLT1EGFRKDRPRKCQPRKCD | |
| SCHEMBL7116962 | 0.88 | FLT1 (0.74) | FLT1EGFRKDRPRKCQPRKCD | |
| SCHEMBL7124468 | 0.84 | FLT1 (0.76) | FLT1EGFRKDRPRKCQPRKCD | |
| SCHEMBL7121036 | 0.84 | FLT1 (0.75) | FLT1EGFRKDRPRKCQPRKCD | |
| SCHEMBL7122674 | 0.83 | EGFR (0.79) | FLT1EGFRKDRPRKCQPRKCD | |
| SCHEMBL7117871 | 0.82 | FLT1 (0.70) | FLT1EGFRKDRPRKCQPRKCD | |
| SCHEMBL7123713 | 0.81 | FLT1 (0.66) | FLT1EGFRKDRPRKCQPRKCD | |
| SCHEMBL7118450 | 0.80 | FLT1 (1.00) | FLT1EGFRKDRPRKCQPRKCD | |
| SCHEMBL7128094 | 0.79 | FLT1 (0.63) | FLT1EGFRKDRPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028964-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | Pfizer Products Inc. (US) | 2000-08-23 | — | — | EP | claimed |
| WO-1999024440-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PRODUCTS INC. (US) | 1999-05-20 | — | — | WO | claimed |