Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LIPA | P38571 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL14921884 | 0.90 | LIPA (0.37) | SHBGHSD11B1LIPAEPHX1APOBEC3A | |
| SCHEMBL579272 | 0.89 | EPHX1 (0.40) | SHBGHSD11B1LIPAEPHX1APOBEC3A | |
| SCHEMBL114150 | 0.89 | EPHX1 (0.40) | SHBGHSD11B1LIPAEPHX1APOBEC3A | |
| SCHEMBL579573 | 0.89 | EPHX1 (0.40) | SHBGHSD11B1LIPAEPHX1APOBEC3A | |
| SCHEMBL29174199 | 0.87 | EPHX1 (0.39) | SHBGHSD11B1LIPAEPHX1APOBEC3A | |
| 1,5-Pentanediol SCHEMBL9996125 | 0.84 | LIPA (0.34) | SHBGHSD11B1LIPAEPHX1ALDH1A1 | |
| SCHEMBL12158781 | 0.82 | EPHX1 (0.36) | SHBGHSD11B1LIPAEPHX1MAPT | |
| Alcohol SCHEMBL28206069 | 0.81 | SHBG (0.52) | SHBGMAPTALDH1A1EPHX2GAA | |
| SCHEMBL4846911 | 0.80 | TSHR (0.43) | SHBGHSD11B1LIPAEPHX1APOBEC3A | |
| SCHEMBL4844027 | 0.80 | TSHR (0.50) | SHBGHSD11B1LIPAEPHX1APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784043-B1 | Transesterification process for the preparation of dihydromyrcenol and myrcenol | QUEST INT (NL) | 2000-03-15 | — | — | EP | claimed |