Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23628388 | 0.79 | ALDH1A1 (0.35) | HPGDALOX15HSD17B10TDP1ALDH1A1 | |
| SCHEMBL27593702 | 0.74 | ALDH1A1 (0.35) | HPGDALOX15HSD17B10TDP1ALDH1A1 | |
| SCHEMBL27761664 | 0.73 | HPGD (0.34) | HPGDALOX15HSD17B10TDP1ALDH1A1 | |
| SCHEMBL29453072 | 0.70 | ALDH1A1 (0.69) | HPGDALOX15HSD17B10TDP1ALDH1A1 | |
| SCHEMBL337585 | 0.70 | ALDH1A1 (0.69) | HPGDALOX15HSD17B10TDP1ALDH1A1 | |
| SCHEMBL12992750 | 0.69 | ALDH1A1 (0.46) | HPGDALOX15HSD17B10TDP1ALDH1A1 | |
| SCHEMBL18822054 | 0.69 | — | — | |
| SCHEMBL21338024 | 0.69 | ALDH1A1 (0.35) | HPGDHSD17B10TDP1ALDH1A1MAPK1 | |
| SCHEMBL22994268 | 0.69 | ALDH1A1 (0.40) | HPGDHSD17B10TDP1ALDH1A1LMNA | |
| SCHEMBL13523400 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000037480-A1 | NOVEL NAPHTHALENE DIOXYGENASE AND METHODS FOR THEIR USE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2000-06-29 | — | — | WO | disclosed |