Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | IL6ST | P40189 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 3/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308822 | 0.90 | NAAA (0.41) | NAAAPPARABRD4PPARGIL6ST | |
| SCHEMBL3308816 | 0.90 | NAAA (0.41) | NAAAPPARABRD4PPARGIL6ST | |
| SCHEMBL16737997 | 0.90 | NAAA (0.41) | NAAAPPARABRD4PPARGIL6ST | |
| SCHEMBL24977629 | 0.88 | NAAA (0.45) | NAAAPPARAPPARGALDH1A1IL6ST | |
| SCHEMBL2553570 | 0.88 | AKR1B1 (0.39) | NAAAPPARA | |
| SCHEMBL8164388 | 0.88 | NAAA (0.38) | NAAAPPARABRD4ALDH1A1IL6ST | |
| SCHEMBL2552573 | 0.88 | AKR1B1 (0.39) | NAAAPPARA | |
| SCHEMBL15092485 | 0.88 | AKR1B1 (0.39) | NAAAPPARA | |
| SCHEMBL3305644 | 0.87 | KDM4E (0.45) | NAAAALDH1A1KDM4ECSNK2BCSNK2A1 | |
| SCHEMBL3305638 | 0.87 | KDM4E (0.45) | NAAAALDH1A1KDM4ECSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079836-A2 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-07-03 | — | — | WO | disclosed |