SCHEMBL81644

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12580658	0.87	ELOVL1 (0.40)	ELOVL1HRH4CYP2C19ACACBMMP8
	SCHEMBL83974	0.85	CYP2C19 (0.42)	ELOVL1HRH4CYP2C19ALDH1A1TSHR
	SCHEMBL82974	0.85	ACACB (0.36)	ELOVL1HRH4CYP2C19KDM4EACACB
	SCHEMBL82959	0.85	ACACB (0.36)	ELOVL1HRH4CYP2C19KDM4EACACB
	SCHEMBL82973	0.85	ACACB (0.36)	ELOVL1HRH4CYP2C19KDM4EACACB
	SCHEMBL84342	0.85	ACACB (0.36)	ELOVL1HRH4CYP2C19KDM4EACACB
	SCHEMBL83494	0.85	ACACB (0.38)	ELOVL1HRH4CYP2C19ACACBADAM17
	SCHEMBL84497	0.85	ELOVL1 (0.51)	ELOVL1HRH4CYP2C19TSHRNPC1
	SCHEMBL82251	0.84	MAP4K4 (0.43)	MAP4K4ELOVL1HRH4ACACB
	SCHEMBL83628	0.83	ELOVL1 (0.52)	ELOVL1HRH4CYP2C19ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.