Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 4/20 | 0.41 |
| ▸ | METAP1 | P53582 | 4/20 | 0.41 |
| ▸ | CBFB | Q13951 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548421 | 1.00 | GAA (0.50) | GAAMEN1POLBBLMUBE2N | |
| SCHEMBL548420 | 0.90 | NISCH (0.46) | GAAMEN1POLBBLMUBE2N | |
| SCHEMBL24312987 | 0.85 | GAA (0.56) | GAAMEN1POLBBLMKMT2A | |
| SCHEMBL24313347 | 0.83 | SCD (0.48) | GAAMEN1POLBBLMKMT2A | |
| SCHEMBL8677423 | 0.82 | NISCH (0.50) | NISCHPRMT1 | |
| SCHEMBL548343 | 0.82 | NISCH (0.50) | NISCHPRMT1 | |
| SCHEMBL548349 | 0.81 | NISCH (0.46) | GAANISCHTSHRPRMT1TOP2A | |
| SCHEMBL21900562 | 0.81 | MEN1 (0.59) | GAAMEN1POLBBLMKMT2A | |
| SCHEMBL21856214 | 0.81 | MEN1 (0.48) | GAAMEN1POLBBLMKMT2A | |
| SCHEMBL24312904 | 0.80 | SCD (0.47) | GAAMEN1POLBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973750-A1 | SUBSTITUTED BENZIMIDAZOLES AND THEIR USE FOR TREATING RETROVIRAL INFECTION | The University of North Carolina at Chapel Hill (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998038170-A1 | SUBSTITUTED BENZIMIDAZOLES AND THEIR USE FOR TREATING RETROVIRAL INFECTION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-09-03 | — | — | WO | disclosed |