Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 11/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548343 | 1.00 | NISCH (0.50) | NISCHPRMT1MAOB | |
| SCHEMBL548420 | 0.92 | NISCH (0.46) | NISCHPRMT1 | |
| SCHEMBL8477890 | 0.89 | NPC1 (0.58) | NISCHPRMT1 | |
| SCHEMBL13204584 | 0.85 | NISCH (0.54) | NISCHPRMT1 | |
| SCHEMBL548359 | 0.84 | NISCH (0.52) | NISCHPRMT1 | |
| SCHEMBL548421 | 0.82 | GAA (0.50) | NISCHPRMT1 | |
| SCHEMBL8164925 | 0.82 | GAA (0.50) | NISCHPRMT1 | |
| SCHEMBL8475087 | 0.82 | NPC1 (0.55) | NISCH | |
| SCHEMBL549218 | 0.82 | TOP2A (0.56) | NISCHPRMT1 | |
| SCHEMBL14599548 | 0.81 | PRMT1 (0.49) | NISCHPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831832-A1 | METHODS OF COMBATTING INFECTIOUS DISEASES USING DICATIONIC BIS-BENZIMIDAZOLES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-04-01 | — | — | EP | disclosed |