Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167144 | 1.00 | ACE (0.47) | ACEMLYCDCPA3FOLH1 | |
| SCHEMBL8159707 | 0.92 | ACE (0.50) | ACE | |
| SCHEMBL8171167 | 0.92 | ACE (0.50) | ACE | |
| SCHEMBL8459593 | 0.92 | ACE (0.50) | ACE | |
| SCHEMBL8161868 | 0.91 | ACE (0.41) | ACEFOLH1 | |
| SCHEMBL8159638 | 0.91 | ACE (0.54) | ACE | |
| SCHEMBL8166795 | 0.90 | ACE (0.53) | ACE | |
| SCHEMBL8166776 | 0.90 | ACE (0.53) | ACE | |
| SCHEMBL8010442 | 0.89 | MMP12 (0.44) | ACE | |
| SCHEMBL8026798 | 0.89 | ACE (0.39) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048852-A | BACTERICIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-04-11 | — | — | US | claimed |
| US-6048852-A | BACTERICIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-04-11 | — | — | US | disclosed |