SCHEMBL8165409

SCHEMBL8165409

C=C(C)C(=O)OC(C)NC(CC)[Si](OC)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10965173 0.93 ALDH1A1 (0.34) ALDH1A1TSHRTHRB
SCHEMBL3281738 0.77 TSHR (0.41) ALDH1A1TSHRTHRB
SCHEMBL4948163 0.77 TSHR (0.41) ALDH1A1TSHRTHRB
SCHEMBL9321911 0.76 ALDH1A1 (0.50) ALDH1A1TSHRTHRB
Hydrochloric Acid SCHEMBL8340990 0.76 TSHR (0.40) ALDH1A1TSHRTHRB
SCHEMBL4276427 0.75
SCHEMBL6575777 0.74 ALDH1A1 (0.40) ALDH1A1TSHRTHRB
SCHEMBL17801655 0.74 ALDH1A1 (0.40) ALDH1A1TSHRTHRB
SCHEMBL25561 0.74 ALDH1A1 (0.40) ALDH1A1TSHRTHRB
SCHEMBL20335510 0.73 ALDH1A1 (0.50) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1043356-A1 Low modulus, one part RTV sealant compositions GENERAL ELECTRIC COMPANY (US) 2000-10-11 EP disclosed
US-5612438-A Curable siloxane polymers containing integral UV absorbers GENERAL ELECTRIC COMPANY (US) 1997-03-18 US disclosed
EP-0598545-A2 Curable siloxane polymers GENERAL ELECTRIC COMPANY (US) 1994-05-25 EP disclosed
US-5310845-A Adding an amine catalyst to a solution of cosolvent-diluted silyated UV agent and polysiloxane/solvent mixture GENERAL ELECTRIC COMPANY (US) 1994-05-10 US disclosed