Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 1.00 |
| ▸ | PIM3 | Q86V86 | 4/20 | 1.00 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 4/20 | 1.00 |
| ▸ | DYRK2 | Q92630 | 1/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.80 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.80 |
| ▸ | GSK3B | P49841 | 3/20 | 0.76 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.76 |
| ▸ | CDC7 | O00311 | 2/20 | 0.76 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.76 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.76 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.76 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.76 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.76 |
| ▸ | CLK2 | P49760 | 2/20 | 0.76 |
| ▸ | GSK3A | P49840 | 2/20 | 0.76 |
| ▸ | NEK4 | P51957 | 2/20 | 0.76 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.76 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15421616 | 1.00 | PIM1 (1.00) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL29377541 | 1.00 | PIM1 (1.00) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL8165608 | 1.00 | PIM1 (1.00) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL1641513 | 0.91 | DYRK1A (0.83) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL8311863 | 0.91 | DYRK1A (0.83) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL8311581 | 0.89 | PDE4B (1.00) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL8311580 | 0.89 | PDE4B (1.00) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL15421525 | 0.89 | PIM1 (1.00) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL1250564 | 0.89 | PIM1 (1.00) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL1250565 | 0.89 | PIM1 (1.00) | PIM1PIM3PIM2DYRK1ADYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2016-04-14 | — | — | US | claimed |
| US-5523314-A | RHODANINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-06-04 | — | — | US | claimed |
| US-12590127-B2 | Split photoactive yellow protein complementation system and uses thereof | PARIS SCIENCES ET LETTRES (FR) | 2026-03-31 | — | — | US | disclosed |
| WO-2024052353-A1 | PROXIMITY INDUCING SYSTEM AND USES THEREOF | SORBONNE UNIVERSITE (FR) | 2024-03-14 | — | — | WO | disclosed |
| US-20220169682-A1 | SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF | PARIS SCIENCES ET LETTRES (FR) | 2022-06-02 | — | — | US | disclosed |
| EP-3947355-A1 | SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF | Paris Sciences et Lettres (FR) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020201538-A1 | SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF | PARIS SCIENCES ET LETTRES – QUARTIER LATIN (FR) | 2020-10-08 | — | — | WO | disclosed |
| EP-3719007-A1 | SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF | Paris Sciences et Lettres - Quartier Latin (FR) | 2020-10-07 | — | — | EP | disclosed |
| US-9896421-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2018-02-20 | — | — | US | disclosed |
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2016-04-14 | — | — | US | disclosed |
| US-9216148-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2015-12-22 | — | — | US | disclosed |
| EP-0915090-A1 | Compounds useful as hypoglycemic agents and for treating Alzheimer's disease | ELI LILLY AND COMPANY (US) | 1999-05-12 | — | — | EP | disclosed |
| US-5731336-A | USING ARYL-SUBSTITUTED RHODAMINES | ELI LILLY AND COMPANY (US) | 1998-03-24 | — | — | US | disclosed |
| US-5716975-A | NONTOXIC RHODANINE DERIVATIVES; ANTIDIABETIC AGENTS, CATHEPSIN D INHIBITORS, B-AMYLOID PROTEIN REDUCTION | ELI LILLY AND COMPANY (US) | 1998-02-10 | — | — | US | disclosed |
| US-5661168-A | ADMINISTERING RHODANINE DERIVATIVES TO CONTROL DIABETES | ELI LILLY AND COMPANY (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1996022772-A1 | METHOD FOR TREATING MULTIPLE SCLEROSIS | ELI LILLY AND COMPANY (US) | 1996-08-01 | — | — | WO | disclosed |
| EP-0722729-A2 | Aryl-substituted rhodanines for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5523314-A | RHODANINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| CN-1091006-A | Chemical compound as blood sugar lowering and treatment degenerative brain disorder | LILLY CO ELI (US) | 1994-08-24 | — | — | CN | disclosed |
| EP-0587377-A2 | Thiazolidinone derivatives as hypoglycemic agents and for treating Alzheimer's disease | ELI LILLY AND COMPANY (US) | 1994-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169682-A1 | SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF | BLVRB, IK, HBG2 | PIM1 4688/4885PIM3 4464/4885PIM2 4475/4885 |
| US-20160102065-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PPARG, PPARA, TYR | PIM1 3858/4885PIM3 3936/4885PIM2 4285/4885 |
| US-12590127-B2 | Split photoactive yellow protein complementation system and uses thereof | BLVRB, HBG2, Q6ZSR9 | PIM1 4773/4885PIM3 4664/4885PIM2 4523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.