Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831204 | 0.86 | GRM2 (1.00) | GRM2 | |
| SCHEMBL8152779 | 0.82 | GRM2 (0.62) | GRM2 | |
| SCHEMBL2830396 | 0.77 | GRM2 (1.00) | GRM2 | |
| SCHEMBL2829844 | 0.74 | GRM2 (0.81) | GRM2 | |
| SCHEMBL2831836 | 0.71 | GRM2 (0.83) | GRM2 | |
| SCHEMBL2186805 | 0.71 | GRM2 (0.65) | GRM2 | |
| SCHEMBL30795860 | 0.71 | GRM2 (0.65) | GRM2 | |
| SCHEMBL2831898 | 0.70 | GRM2 (0.73) | GRM2 | |
| SCHEMBL8167358 | 0.68 | GRM2 (0.51) | GRM2 | |
| SCHEMBL8157229 | 0.66 | GRM2 (0.49) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107480-A1 | 1,4-DISUBSTITUTED 3-CYANO-PYRIDONE DERIVATIVES AND THEIR USE AS POSITIVE MGLUR2 -RECEPTOR MODULATORS | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC (US) | 2008-09-12 | — | — | WO | disclosed |