SCHEMBL8166207

SCHEMBL8166207

COC(=O)C(CC(C)C)(CC(C)C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.38
PTPN1 P18031 2/20 0.36
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
GRM2 Q14416 1/20 0.33
GRM3 Q14832 1/20 0.33
KCNN4 O15554 1/20 0.32
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.31
DGAT1 O75907 1/20 0.31
AR P10275 1/20 0.31
PTPRB P23467 2/20 0.31
PTPN2 P17706 1/20 0.31
PTPRA P18433 1/20 0.31
FPR2 P25090 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234361 0.89 MMP8 (0.41) MMP8PTPN1CYP2D6CYP2C19KCNN4
SCHEMBL2139826 0.81 GRM2 (0.39) CYP2D6CYP2C19GRM2GRM3GAA
SCHEMBL3896850 0.79 GRM2 (0.36) MMP8CYP2D6CYP2C19GRM2GRM3
SCHEMBL28132221 0.79 MMP8 (0.40) MMP8
SCHEMBL28167346 0.79 MMP8 (0.40) MMP8
SCHEMBL9364104 0.79 MMP8 (0.51) MMP8CYP2C19GAASMN1; SMN2MAPT
SCHEMBL7624691 0.77 GRM2 (0.35) MMP8CYP2D6CYP2C19GRM2GRM3
SCHEMBL3942873 0.77 MMP8 (0.49) MMP8CYP2D6CYP2C19GRM2GRM3
SCHEMBL8200011 0.77 MMP8 (0.37) MMP8CYP2D6CYP2C19GRM2GRM3
SCHEMBL221073 0.77 PTPN1 (0.40) PTPN1KCNN4GAADGAT1PTPRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN claimed
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN disclosed
CN-113912755-A Catalyst composition for olefin polymerization and application thereof 张一锴 2022-01-11 CN disclosed
CN-109694420-B Catalyst system for olefin polymerization, prepolymerized catalyst and olefin polymerization process 中国石油化工股份有限公司 2021-08-03 CN disclosed
EP-0737697-B1 Process for producing cycloolefin random copolymers MITSUI CHEMICALS INC (JP) 2000-01-12 EP disclosed
EP-0579342-B1 Process for producing cycloolefin random copolymers MITSUI PETROCHEMICAL IND (JP) 1997-02-12 EP disclosed
EP-0737697-A2 Process for producing cycloolefin random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-10-16 EP disclosed
EP-0358516-B1 Process for producing cycloolefin random copolymers MITSUI PETROCHEMICAL IND (JP) 1994-12-07 EP disclosed
US-5310801-A Catalytic copolymerization with ethylene; flash drying MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-05-10 US disclosed
EP-0579342-A2 Process for producing cycloolefin random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-01-19 EP disclosed
US-5243005-A Process for producing cycloolefin random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-09-07 US disclosed
US-5128446-A With ethylene MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-07-07 US disclosed
EP-0358516-A2 Process for producing cycloolefin random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-03-14 EP disclosed