SCHEMBL8166263

SCHEMBL8166263

C=CC(Oc1ccc(CC)cc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
TP53 P04637 1/20 0.42
FFAR1 O14842 1/20 0.40
SLC7A5 Q01650 3/20 0.40
F2 P00734 2/20 0.39
RAB9A P51151 1/20 0.39
CASR P41180 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
PRSS1 P07477 1/20 0.35
BCHE P06276 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4865335 0.86 SRD5A2 (0.42) FFAR1SLC7A5SLC6A2SLC6A4SLC6A3
SCHEMBL3291158 0.82 SLC6A4 (0.39) SLC7A5CASRSLC6A4
SCHEMBL3294416 0.81 CA4 (0.46) PPARGPPARATP53RAB9AMEN1
SCHEMBL3294031 0.81 NPSR1 (0.41) PPARGPPARASLC7A5MEN1KMT2A
SCHEMBL8163510 0.80 CYP1A2 (0.42) PPARGPPARASLC7A5
SCHEMBL7229364 0.78 SLC7A5 (0.48) PPARGPPARATP53SLC7A5F2
SCHEMBL14114020 0.77 FFAR1 (0.62) PPARGPPARATP53FFAR1F2
Ammonia Solution, Strong SCHEMBL8698858 0.77 F2 (0.56) PPARGPPARATP53FFAR1F2
SCHEMBL3299568 0.77 SLC6A4 (0.46) SLC7A5MEN1KMT2ASLC6A2SLC6A4
SCHEMBL3295214 0.77 SLC6A4 (0.46) PPARGPPARASLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890615-B1 High temperature crosslinkable liquid crystalline polyester compositions DAINIPPON INK & CHEMICALS (JP) 2000-05-03 EP disclosed