Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 10/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 7/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160338 | 0.86 | ANPEP (0.44) | S1PR1S1PR3S1PR4S1PR2ANPEP | |
| SCHEMBL8465177 | 0.77 | MAOB (0.41) | S1PR1S1PR3S1PR2MAOB | |
| SCHEMBL8465173 | 0.76 | MAOB (0.40) | S1PR1S1PR3S1PR2MAOB | |
| SCHEMBL9163250 | 0.75 | ANPEP (0.41) | S1PR1S1PR3S1PR4S1PR2ANPEP | |
| SCHEMBL9472755 | 0.67 | MAOB (0.50) | MAOB | |
| SCHEMBL3544544 | 0.67 | MAOB (0.53) | S1PR1S1PR3S1PR2MAOB | |
| SCHEMBL10636838 | 0.66 | MAOB (0.48) | MAOB | |
| SCHEMBL8697867 | 0.65 | S1PR2 (0.47) | S1PR1S1PR3S1PR4S1PR2MAOB | |
| SCHEMBL8269268 | 0.65 | MAOB (0.50) | MAOB | |
| SCHEMBL7056724 | 0.65 | MAOB (0.50) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642519-B1 | SULFUR-CONTAINING PHOSPONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 2000-08-09 | — | — | EP | disclosed |
| EP-0650361-A1 | COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-05-03 | — | — | EP | disclosed |
| EP-0642519-A1 | SULFUR-CONTAINING PHOSPONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS (US) | 1995-03-15 | — | — | EP | disclosed |
| WO-1994000130-A1 | COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| WO-1993024496-A1 | SULFUR-CONTAINING PHOSPONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |