Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467310 | 0.84 | KMT2A (0.54) | MEN1HPGDKMT2ATSHR | |
| SCHEMBL8465173 | 0.83 | MAOB (0.40) | MAOBGFERTSHRS1PR2S1PR1 | |
| SCHEMBL8166284 | 0.77 | S1PR1 (0.38) | MAOBS1PR2S1PR1S1PR3 | |
| SCHEMBL10636838 | 0.76 | MAOB (0.48) | MAOBGFERITGB1ITGA5MAOA | |
| SCHEMBL7056724 | 0.74 | MAOB (0.50) | MAOBGFERTSHRMAOA | |
| SCHEMBL11244317 | 0.74 | GFER (0.54) | MAOBGFERTSHRGRIN2DGRIN2A | |
| SCHEMBL7188715 | 0.73 | KMT2A (0.56) | MEN1HPGDKMT2ATSHR | |
| SCHEMBL9472755 | 0.73 | MAOB (0.50) | MAOBGFERMAOAHSD17B10ESRRG | |
| SCHEMBL3544544 | 0.73 | MAOB (0.53) | MAOBGFERS1PR2S1PR1MAOA | |
| SCHEMBL19674075 | 0.73 | GFER (0.48) | MAOBGFERTSHRITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869471-A | Methods for the treatment of arthritis using phosphonates and NSAIDS | THE PROCTOR & GAMBLE COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5824661-A | TREATMENT OF OSTEOPOROSIS, OSTEOARTHRITIS, RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-20 | — | — | US | disclosed |