Baicalin

Baicalin

SCHEMBL8166294

O=C(O)[C@H]1O[C@H](Oc2cc3oc(-c4ccccc4)cc(=O)c3c(O)c2O)[C@H](O)[C@@H](O)[C@@H]1O.O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.93
HPGD P15428 4/20 0.93
KDM1A O60341 4/20 0.93
CDK1 P06493 3/20 0.93
CCNB1 P14635 3/20 0.93
MEN1 O00255 3/20 0.93
MAPT P10636 3/20 0.93
KMT2A Q03164 3/20 0.93
XDH P47989 3/20 0.93
GABRP O00591 2/20 0.93
GABRD O14764 2/20 0.93
GAPDH P04406 2/20 0.93
CYP1A2 P05177 2/20 0.93
GABRA1 P14867 2/20 0.93
GABRB1 P18505 2/20 0.93
GABRG2 P18507 2/20 0.93
GABRB3 P28472 2/20 0.93
GABRA5 P31644 2/20 0.93
GABRA3 P34903 2/20 0.93
GABRA2 P47869 2/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Baicalin SCHEMBL6422596 0.99 ALDH1A1 (0.91) ALDH1A1HPGDKDM1ACDK1CCNB1
Baicalin SCHEMBL285081 0.96 ALDH1A1 (1.00) ALDH1A1HPGDKDM1ACDK1CCNB1
Baicalin SCHEMBL13853421 0.96 ALDH1A1 (1.00) ALDH1A1HPGDKDM1ACDK1CCNB1
Baicalin SCHEMBL4649420 0.96 ALDH1A1 (1.00) ALDH1A1HPGDKDM1ACDK1CCNB1
Baicalin SCHEMBL17915839 0.96 ALDH1A1 (1.00) ALDH1A1HPGDKDM1ACDK1CCNB1
Baicalin SCHEMBL13853350 0.96 ALDH1A1 (1.00) ALDH1A1HPGDKDM1ACDK1CCNB1
Baicalin SCHEMBL285082 0.96 ALDH1A1 (1.00) ALDH1A1HPGDKDM1ACDK1CCNB1
Baicalin SCHEMBL21869123 0.96 ALDH1A1 (1.00) ALDH1A1HPGDKDM1ACDK1CCNB1
Baicalin SCHEMBL21335295 0.96 ALDH1A1 (1.00) ALDH1A1HPGDKDM1ACDK1CCNB1
Baicalin SCHEMBL29349819 0.96 ALDH1A1 (1.00) ALDH1A1HPGDKDM1ACDK1CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116115540-B Skin anti-aging composition, application and daily chemical product 广东雅丽洁精细化工有限公司 2023-10-24 CN disclosed
CN-116115540-A Skin anti-aging composition, application and daily chemical product 广东雅丽洁精细化工有限公司 2023-05-16 CN disclosed
CN-112274504-A Application of Baikeli in preparation of medicine for treating diseases caused by intestinal flora disorder 中国医学科学院药物研究所 2021-01-29 CN disclosed
CN-112057498-A Processing method and application of scutellaria baicalensis stir-fried with wine 南京中山制药有限公司 2020-12-11 CN disclosed
EP-3600305-A1 BERBERINE ALKALOID FORMULATIONS IN THE PREVENTION AND/OR TREATMENT OF INFECTIOUS DISEASE IRP Health Pty Ltd (AU) 2020-02-05 EP disclosed
WO-2018176093-A1 BERBINE ALKALOID FORMULATIONS IN THE PREVENTION AND/OR TREATMENT OF INFECTIOUS DISEASE IRICCORGPHARM PTY LTD (AU) 2018-10-04 WO disclosed
EP-0973523-A1 ANTI-MICROBIAL PRODUCT Richards, Robert Michael Edward (GB) 2000-01-26 EP disclosed
WO-1998036750-A1 ANTI-MICROBIAL PRODUCT BTG INTERNATIONAL LIMITED (GB) 1998-08-27 WO disclosed