Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814793 | 0.81 | TDP1 (0.32) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL1160665 | 0.79 | TDP1 (0.31) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL2716961 | 0.78 | PTGS1 (0.32) | — | |
| SCHEMBL3360268 | 0.78 | PTGS1 (0.32) | — | |
| SCHEMBL23244687 | 0.72 | LMNA (0.37) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL553467 | 0.72 | LMNA (0.37) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL553468 | 0.72 | LMNA (0.37) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL2317312 | 0.72 | LMNA (0.37) | TDP1LMNAALOX15BLMPMP22 | |
| SCHEMBL2828713 | 0.70 | LMNA (0.35) | TDP1LMNAALOX15BLMPMP22 | |
| Bromide SCHEMBL31058038 | 0.70 | LMNA (0.35) | TDP1LMNAALOX15BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6045697-A | PREVENTING NON-SPECIFIC INTERACTIONS BETWEEN PROTEINS ETC. AND THE CHROMATOGRAPHIC SUPPORT BY FILLING THE MATRIX PORES WITH A POLYMER GEL TO FORM A RECEPTIVE THREE-DIMENSIONAL POLYMER NETWORK DEACTIVATING INNATE SUPPORT SURFACE GROUPS | LIFE TECHNOLOGIES, INC. (US) | 2000-04-04 | — | — | US | disclosed |
| US-5599453-A | POROUS MINERAL OXIDE SUBSTRATE MATRIX, THREE-DIMENSIONAL POLYMER GEL NETWORK; FOR SEPARATION OF BIOMOLECULES | BIOSEPRA INC. (US) | 1997-02-04 | — | — | US | disclosed |
| US-5593576-A | CHROMATOGRAPHY | BIOSEPRA, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| US-5362859-A | Immobilized ligand proteins, chromatography | SEPRACOR, INC. (US) | 1994-11-08 | — | — | US | disclosed |