Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PPARA | Q07869 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | APAF1 | O14727 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696303 | 0.99 | TSHR (0.64) | TSHRPPARAPPARGHTTMAPT | |
| SCHEMBL11847623 | 0.91 | PPARA (0.59) | TSHRPPARAPPARGHTTMAPT | |
| SCHEMBL586998 | 0.89 | HTT (0.53) | TSHRPPARAPPARGHTTMAPT | |
| SCHEMBL586997 | 0.87 | HTT (0.52) | TSHRPPARAPPARGHTTMAPT | |
| SCHEMBL10396115 | 0.87 | HTT (0.52) | TSHRPPARAPPARGHTTMAPT | |
| SCHEMBL7813434 | 0.86 | HTT (0.60) | TSHRPPARAPPARGHTTMAPT | |
| SCHEMBL28381703 | 0.85 | HTT (0.59) | TSHRPPARAPPARGHTTMAPT | |
| SCHEMBL11576732 | 0.84 | TSHR (0.64) | TSHRPPARAPPARGMAPTTHRB | |
| SCHEMBL2542877 | 0.83 | LTB4R (0.62) | PPARAPPARGHTTMAPTMAPK1 | |
| SCHEMBL11403641 | 0.83 | MAPT (0.63) | TSHRPPARAPPARGMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769487-B1 | Process for preparing carboxyl groups containing alkyl aryl ethers | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| US-5869735-A | Process for the preparation of alkyl aryl ethers containing carboxyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-09 | — | — | US | disclosed |
| EP-0769487-A2 | Process for preparing carboxyl groups containing alkyl aryl ethers | BAYER AG (DE) | 1997-04-23 | — | — | EP | disclosed |