Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13502724 | 0.89 | CTSB (0.39) | CTSBCTSS | |
| SCHEMBL996662 | 0.88 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL13502613 | 0.88 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL996664 | 0.88 | CTSB (0.41) | CTSBCTSS | |
| SCHEMBL15159923 | 0.87 | CTSB (0.44) | CTSBCTSS | |
| SCHEMBL2843883 | 0.86 | CTSB (0.42) | CTSBCTSS | |
| SCHEMBL1927692 | 0.84 | CTSB (0.46) | CTSBCTSS | |
| SCHEMBL11929778 | 0.84 | CTSB (0.46) | CTSBCTSS | |
| SCHEMBL6844970 | 0.84 | CTSB (0.46) | CTSBCTSS | |
| SCHEMBL3045942 | 0.83 | CTSB (0.42) | CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111396-B1 | HCV INHIBITING MACROCYCLIC PHENYLCARBAMATES | JANSSEN R & D IRELAND (IE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2008096001-A1 | HCV INHIBITING MACROCYCLIC PHENYLCARBAMATES | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-14 | — | — | WO | disclosed |