Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154141 | 0.94 | TSHR (0.46) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL8154413 | 0.94 | TSHR (0.50) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL8162315 | 0.90 | CYP3A4 (0.46) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL8167202 | 0.83 | CYP4F2 (0.44) | ATMCA2L3MBTL1CA1MMP8 | |
| SCHEMBL8154123 | 0.81 | CYP3A4 (0.47) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL8162773 | 0.80 | CYP3A4 (0.48) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL29004158 | 0.78 | CYP3A4 (0.55) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL8154578 | 0.78 | CYP3A4 (0.46) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL5441371 | 0.76 | CYP3A4 (0.50) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL8161094 | 0.76 | CYP3A4 (0.50) | TSHRCYP3A4TDP1ATMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121483-A | 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin | SHOWA DENKO K.K. (JP) | 2000-09-19 | — | — | US | disclosed |
| US-6118019-A | 3-alkoxypropionic ester derivative | SHOWA DENKO K.K. (JP) | 2000-09-12 | — | — | US | disclosed |
| US-6015867-A | MIXTURES OF ORGANOALUMINUM COMPOUNDS, MAGNESIUM, TITANIUM AND HALOGEN COMPOUNDS WITH ELECTRON DONOR ESTER AS INTENSIFIER, NONTOXIC, SAFE, EFFICIENT | SHOWA DENKO K.K. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0704424-B1 | 3-Alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin | SHOWA DENKO KK (JP) | 1998-12-30 | — | — | EP | disclosed |
| EP-0704424-A1 | 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | disclosed |