SCHEMBL8167202

SCHEMBL8167202

CCCCC(COC)(CC(C)C)C(=O)OCC

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.44
CYP4A11 Q02928 2/20 0.44
MMP8 P22894 1/20 0.42
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
THRB P10828 1/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.33
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820209 0.87 MMP8 (0.49) CYP4F2CYP4A11MMP8MEN1KMT2A
SCHEMBL8163198 0.87 CYP4F2 (0.43) CYP4F2CYP4A11MMP8MEN1KMT2A
SCHEMBL18050411 0.87 CYP4F2 (0.43) CYP4F2CYP4A11MMP8MEN1KMT2A
SCHEMBL8163550 0.86 MMP8 (0.43) CYP4F2CYP4A11MMP8MEN1KMT2A
SCHEMBL8167181 0.83 TSHR (0.47) MMP8ATML3MBTL1CA1CA2
SCHEMBL18050521 0.79 CYP4F2 (0.42) CYP4F2CYP4A11MMP8MEN1KMT2A
SCHEMBL18050433 0.79 CYP4F2 (0.42) CYP4F2CYP4A11MMP8MEN1KMT2A
SCHEMBL18050380 0.77 MMP8 (0.43) CYP4F2CYP4A11MMP8MEN1KMT2A
SCHEMBL8734861 0.77 CYP4F2 (0.38) CYP4F2CYP4A11MMP8MEN1KMT2A
SCHEMBL8154141 0.76 TSHR (0.46) MMP8ATML3MBTL1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6121483-A 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin SHOWA DENKO K.K. (JP) 2000-09-19 US disclosed
US-6118019-A 3-alkoxypropionic ester derivative SHOWA DENKO K.K. (JP) 2000-09-12 US disclosed
US-6015867-A MIXTURES OF ORGANOALUMINUM COMPOUNDS, MAGNESIUM, TITANIUM AND HALOGEN COMPOUNDS WITH ELECTRON DONOR ESTER AS INTENSIFIER, NONTOXIC, SAFE, EFFICIENT SHOWA DENKO K.K. (JP) 2000-01-18 US disclosed
EP-0704424-B1 3-Alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin SHOWA DENKO KK (JP) 1998-12-30 EP disclosed
EP-0704424-A1 3-alkoxypropionic ester derivative, olefin polymerization catalyst, and process for preparation of polyolefin SHOWA DENKO KABUSHIKI KAISHA (JP) 1996-04-03 EP disclosed