SCHEMBL8167196

SCHEMBL8167196

CCCC(O)C(O)C1CCCNC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 2/20 0.41
CPB2 Q96IY4 2/20 0.41
SLC6A1 P30531 2/20 0.32
KCNH2 Q12809 1/20 0.32
SLC6A11 P48066 1/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLC6A13 Q9NSD5 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
NOS2 P35228 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10608177 0.82 CPN1 (0.44) CPN1CPB2SLC6A1KCNH2SLC6A11
SCHEMBL4290504 0.76 CPN1 (0.41) CPN1CPB2NOS2
SCHEMBL4290481 0.76 CPN1 (0.41) CPN1CPB2NOS2
SCHEMBL19514764 0.76 CPN1 (0.43) CPN1CPB2SLC6A1SLC6A11TSHR
SCHEMBL7128001 0.76 CPN1 (0.43) CPN1CPB2SLC6A1SLC6A11TSHR
SCHEMBL29333023 0.76 CPN1 (0.43) CPN1CPB2SLC6A1SLC6A11TSHR
SCHEMBL25395272 0.75 CPN1 (0.40) CPN1CPB2KCNH2TSHRLMNA
SCHEMBL13259733 0.75 CPN1 (0.40) CPN1CPB2KCNH2
SCHEMBL27468423 0.75 CPN1 (0.44) CPN1CPB2SLC6A1KCNH2SLC6A11
SCHEMBL10608121 0.75 CPN1 (0.41) CPN1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6057337-A USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS SHISEIDO CO., LTD. (JP) 2000-05-02 US disclosed
EP-0933361-A1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO COMPANY LIMITED (JP) 1999-08-04 EP disclosed