SCHEMBL8167263

SCHEMBL8167263

Oc1ccc(S)nn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29723088 0.80
SCHEMBL29740320 0.80
SCHEMBL7770425 0.80
SCHEMBL154932 0.80
SCHEMBL22960695 0.77
SCHEMBL22960697 0.77
Ammonia Solution, Strong SCHEMBL22960694 0.77
SCHEMBL13990886 0.65
SCHEMBL428878 0.65
SCHEMBL10480517 0.65 BCAT2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022245-A2 Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation CIBA-GEIGY AG (CH) 1981-01-14 EP claimed
JP-57046967-A None JP disclosed
JP-57048986-A None JP disclosed
JP-57197282-A None JP disclosed
WO-2000020441-A2 CYCLIC PEPTIDES AS ANTIFUNGAL AGENTS ABBOTT LABORATORIES (US) 2000-04-13 WO disclosed
US-RE35754-E FOR TREATING BACTERIAL INFECTIONS HOECHST AKTIENGESELLSCHAFT (DE) 1998-03-24 US disclosed
US-5710146-A ANTIBIOTICS FOR BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-20 US disclosed
EP-0644881-B1 3-PYRIDAZINE DERIVATIVES AND THEIR USE IN RUBBER MONSANTO CO (US) 1997-07-30 EP disclosed
EP-0726255-A2 3-Pyridazine derivatives and their use in rubber MONSANTO COMPANY (US) 1996-08-14 EP disclosed
EP-0371312-B1 Benzoxazine derivatives MERCK PATENT GMBH (DE) 1994-07-20 EP disclosed
US-4252948-A PYRIDAZINYL FARMITALIA CARLO ERBA S.P.A. (IT) 1981-02-24 US disclosed
EP-0022245-A2 Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation CIBA-GEIGY AG (CH) 1981-01-14 EP disclosed
US-4234578-A ANTIBIOTICS CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed
EP-0017238-A1 Cephalosporin derivatives and process for their preparation and pharmaceutical compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1980-10-15 EP disclosed
EP-0016900-A1 Intermediates in the preparation of cephalosporin derivatives, process for their preparation and use CIBA-GEIGY AG (CH) 1980-10-15 EP disclosed
EP-0003960-A1 6-Substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1979-09-19 EP disclosed
US-4166911-A Pyridazinyl-ergoline compounds having neuroleptic activity FARMITALIA CARLO ERBA S.P.A. (IT) 1979-09-04 US disclosed
US-4144391-A REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE ELI LILLY AND COMPANY (US) 1979-03-13 US disclosed
EP-0000500-A2 Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1979-02-07 EP disclosed
US-3946000-A BACTERICIDES, POULTRY, ANIMALS BRISTOL-MYERS COMPANY (US) 1976-03-23 US disclosed