Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641890 | 0.86 | — | — | |
| SCHEMBL912414 | 0.83 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2TP53 | |
| SCHEMBL27734871 | 0.83 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2TP53 | |
| SCHEMBL28210539 | 0.83 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2TP53 | |
| SCHEMBL911353 | 0.83 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2TP53 | |
| SCHEMBL11861848 | 0.83 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2TP53 | |
| Hydrochloric Acid SCHEMBL6673110 | 0.83 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2TP53 | |
| SCHEMBL912568 | 0.83 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2TP53 | |
| SCHEMBL28772165 | 0.83 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2TP53 | |
| Fluoride SCHEMBL27987761 | 0.83 | TDP1 (0.50) | CYP3A4TDP1ESR1ESR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138039-A1 | COMPOSITION FOR CURING-REACTIVE SILICONE ADHESIVE AGENT, CURED PRODUCT OF SAME, AND USES FOR THESE | ダウ・東レ株式会社 | 2020-07-02 | — | — | WO | disclosed |
| US-6127301-A | Catalyst system and method for reaction of olefin | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-03 | — | — | US | disclosed |