Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.72 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.72 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.72 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.55 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SCARB1 | Q8WTV0 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8176712 | 0.99 | SLC6A1 (0.70) | SLC6A1SLC6A12SLC6A11SMPD1SLC6A13 | |
| SCHEMBL8182586 | 0.84 | SLC6A1 (1.00) | SLC6A1SLC6A12SLC6A11SMPD1SLC6A13 | |
| Hydrochloric Acid SCHEMBL8175474 | 0.83 | SLC6A1 (0.98) | SLC6A1SLC6A12SLC6A11SMPD1SLC6A13 | |
| SCHEMBL8174686 | 0.74 | SLC6A1 (0.80) | SLC6A1SLC6A12SLC6A11SMPD1SLC6A13 | |
| SCHEMBL6263349 | 0.71 | SMPD1 (1.00) | SLC6A1SLC6A12SLC6A11SMPD1SIGMAR1 | |
| SCHEMBL4293184 | 0.70 | SLC6A1 (1.00) | SLC6A1SLC6A12SLC6A11SMPD1SLC6A13 | |
| SCHEMBL29462287 | 0.70 | SLC6A1 (1.00) | SLC6A1SLC6A12SLC6A11SMPD1SLC6A13 | |
| SCHEMBL8174303 | 0.70 | SLC6A1 (0.76) | SLC6A1SLC6A12SLC6A11SLC6A13SIGMAR1 | |
| Hydrochloric Acid SCHEMBL30286393 | 0.70 | SLC6A1 (0.98) | SLC6A1SLC6A12SLC6A11SLC6A13SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8178596 | 0.70 | SLC6A1 (0.98) | SLC6A1SLC6A12SLC6A11SLC6A13SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071932-A | SUPPRESSING ABSORPTION OF GAMMA-AMINOBUTYRIC ACID FOR TREATMENT OF NERVOUS SYSTEM DISORDERS | BRITISH TECHNOLOGY GROUP INTERCORPORATE LICENSING LIMITED (GB) | 2000-06-06 | — | — | US | claimed |
| EP-0823905-A1 | NOVEL HETEROCYCLIC CHEMISTRY | NOVO NORDISK A/S (DK) | 1998-02-18 | — | — | EP | claimed |
| WO-1996034863-A1 | NOVEL HETEROCYCLIC CHEMISTRY | NOVO NORDISK A/S (DK) | 1996-11-07 | — | — | WO | claimed |