Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498037 | 0.85 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL2500874 | 0.85 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL18734657 | 0.84 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL16277882 | 0.84 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL16284010 | 0.82 | HCRTR1 (0.90) | HCRTR1HCRTR2 | |
| SCHEMBL16277955 | 0.79 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL15184183 | 0.79 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL18734896 | 0.79 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL18734704 | 0.79 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL15184179 | 0.79 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008150364-A1 | CYCLOPROPYL PYRROLIDINE OREXIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2008-12-11 | — | — | WO | disclosed |