Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.51 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.50 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | S100B | P04271 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8176919 | 0.99 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| SCHEMBL8179338 | 0.96 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| Acetic Acid SCHEMBL1715435 | 0.93 | PRSS1 (0.54) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| SCHEMBL12461526 | 0.91 | PRSS1 (0.61) | PRSS1TMPRSS2PRMT1F2ST14 | |
| Acetic Acid SCHEMBL1714330 | 0.91 | PRSS1 (0.51) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| Acetic Acid SCHEMBL5624159 | 0.89 | PRMT1 (0.56) | PRSS1TMPRSS2PRMT1F2ST14 | |
| Acetic Acid SCHEMBL1715158 | 0.89 | PRSS1 (0.56) | ITGB3ITGA2BPRSS1TMPRSS2PRMT1 | |
| SCHEMBL14367384 | 0.89 | PRSS1 (0.58) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL1714662 | 0.88 | PRMT1 (0.63) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL14367381 | 0.87 | PRSS1 (0.64) | PRSS1TMPRSS2PRMT1F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153613-A | 2,3-diketopiperazine derivatives or their salts | TOYOMA CHEMICAL CO., LTD. (JP) | 2000-11-28 | — | — | US | disclosed |
| EP-0805149-A1 | NOVEL 2,3-DIKETOPIPERAZINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |