Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.63 |
| ▸ | ITGAV | P06756 | 14/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.63 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 8/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8168263 | 1.00 | ITGB3 (0.63) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL7369516 | 0.84 | ITGB3 (0.48) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL8179651 | 0.83 | ITGAV (0.63) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL8179647 | 0.83 | ITGAV (0.63) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL8176082 | 0.83 | ITGAV (0.65) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6495549 | 0.82 | ITGAV (0.63) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| Acetic Acid SCHEMBL6504819 | 0.80 | ITGAV (0.61) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL8176077 | 0.78 | ITGAV (0.46) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL7403221 | 0.78 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7369530 | 0.78 | ITGB3 (0.41) | ITGB3ITGAVITGA2BITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | claimed |
| US-6153628-A | 1,3,4-thiadiazoles and 1,3,4-Oxadiazoles as αv β3 antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-28 | — | — | US | disclosed |