Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 4/20 | 0.72 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | PGR | P06401 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | IL6 | P05231 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | GLUL | P15104 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206109 | 1.00 | G6PD (0.72) | G6PDSERPINA6HIF1ACYP3A4HSD17B10 | |
| SCHEMBL193712 | 1.00 | G6PD (0.72) | G6PDSERPINA6HIF1ACYP3A4HSD17B10 | |
| SCHEMBL18994229 | 1.00 | G6PD (0.72) | G6PDSERPINA6HIF1ACYP3A4HSD17B10 | |
| SCHEMBL5609666 | 1.00 | G6PD (0.72) | G6PDSERPINA6HIF1ACYP3A4HSD17B10 | |
| SCHEMBL93788 | 1.00 | G6PD (0.72) | G6PDSERPINA6HIF1ACYP3A4HSD17B10 | |
| SCHEMBL29450746 | 1.00 | G6PD (0.72) | G6PDSERPINA6HIF1ACYP3A4HSD17B10 | |
| SCHEMBL2510061 | 1.00 | G6PD (0.72) | G6PDSERPINA6HIF1ACYP3A4HSD17B10 | |
| SCHEMBL21328342 | 1.00 | G6PD (0.72) | G6PDSERPINA6HIF1ACYP3A4HSD17B10 | |
| SCHEMBL21973841 | 1.00 | G6PD (0.72) | G6PDSERPINA6HIF1ACYP3A4HSD17B10 | |
| SCHEMBL14983069 | 0.88 | G6PD (0.58) | G6PDSERPINA6CYP3A4CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080407-A | CYTOKINE-MEDIATED TOXICITY COMPRISING ADMINISTERING TO A PATIENT AN EFFECTIVE AMOUNT OF AN ANTI-MACROPHAGE MIGRATION INHIBITORY FACTOR; GRAFT VERSUS HOST DISEASE, ANTISHOCK, -INFLAMMATORY AGENTS; AUTOIMMUNE DISEASES; | THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) | 2000-06-27 | — | — | US | disclosed |