⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718351 | 0.72 | TSHR (0.50) | — | |
| SCHEMBL28082245 | 0.69 | — | — | |
| SCHEMBL2587475 | 0.67 | — | — | |
| SCHEMBL27372650 | 0.67 | — | — | |
| SCHEMBL29421629 | 0.67 | — | — | |
| SCHEMBL754334 | 0.65 | TDP1 (0.31) | — | |
| SCHEMBL1670 | 0.65 | — | — | |
| SCHEMBL14861 | 0.64 | TDP1 (1.00) | — | |
| SCHEMBL28236221 | 0.64 | TDP1 (1.00) | — | |
| SCHEMBL11689973 | 0.62 | TSHR (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1078 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103987747-B | Unsaturated polyester resin composition and sealed motor | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2015-12-09 | — | — | CN | claimed |
| US-3953416-A | Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same | FOLKERS KARL | 1976-04-27 | — | — | US | claimed |
| US-20240218017-A1 | PEPTIDE AMPHIPHILES WITH MODIFIED DEGRADING SEQUENCES AND METHODS OF USE THEREOF | Endomimetics LLC | 2024-07-04 | — | — | US | disclosed |
| US-20240199698-A1 | PEPTIDE AMPHIPHILE COMPOSITIONS AND METHODS OF USE THEREOF | Endomimetics LLC | 2024-06-20 | — | — | US | disclosed |
| US-20240182574-A1 | ANTIBODIES TO PROGRAMMED CELL DEATH PROTEIN 1 THAT ARE PD-1 AGONISTS | Georgiamune Inc. | 2024-06-06 | — | — | US | disclosed |
| WO-2024119068-A2 | S100A7 AS A DIAGNOSTIC MARKER AND THERAPEUTIC TARGET FOR DISORDERS | OHIO STATE INNOVATION FOUNDATION (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024102807-A2 | IMMUNE CHECKPOINT INHIBITOR AND EXTRACELLULAR MATRIX COMPONENT BINDER COMBINATION THERAPY AND METHODS OF USE THEREOF | NEXTCURE, INC. (US) | 2024-05-16 | — | — | WO | disclosed |
| US-20240150397-A1 | TARGETED DELIVERY SYSTEM AND METHODS OF USE THEREFOR | Sanford Burnham Prebys Medical Discovery Institute | 2024-05-09 | — | — | US | disclosed |
| US-20240148901-A1 | COMPOSITIONS AND METHODS FOR PROPHYLAXIS OF HIV | GEORGIA TECH RESEARCH CORPORATION (US) | 2024-05-09 | — | — | US | disclosed |
| US-20240141305-A1 | HSD17B13 VARIANTS AND USES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2024-05-02 | — | — | US | disclosed |
| EP-3743447-B1 | B7-H4 ANTIBODIES AND METHODS OF USE THEREOF | NEXTCURE INC (US) | 2024-03-27 | — | — | EP | disclosed |
| US-4855454-A | CHEMICAL INTERMEDIATES; SWEETENERS | PFIZER INC. (US) | 1989-08-08 | — | — | US | disclosed |
| US-4665016-A | QUANTITATIVE DETERMINATION OF ENDOPROTEASE | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1987-05-12 | — | — | US | disclosed |
| EP-0200404-A2 | Solid phase process for synthesizing peptides | ALPHA-1 BIOMEDICALS, INC. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4238390-A | Synthesis and biological activity of [D-Thr2, Δ3 Pro5 ]-enkephalinamide | HOFFMANN-LA ROCHE INC. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4148788-A | Synthesis of thymosin α1 | HOFFMANN-LA ROCHE INC. (US) | 1979-04-10 | — | — | US | disclosed |
| US-4116951-A | [Asn2 ]-thymosin α1 and analogs thereof | HOFFMANN-LA ROCHE INC. (US) | 1978-09-26 | — | — | US | disclosed |
| US-4101464-A | Process for preparing foamed solids using two or more azo compounds | PENNWALT CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |
| US-4029615-A | AZO COMPOUNDS | PENNWALT CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |
| US-3993609-A | ACID SENSITIVE AZO PROMOTERS | PENNWALT CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |