SCHEMBL8169097

SCHEMBL8169097

Cc1ccc(S(N)(=O)=O)cc1CC(C)C

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.43
CA2 P00918 7/20 0.42
CA1 P00915 5/20 0.42
CA9 Q16790 4/20 0.42
CA12 O43570 3/20 0.42
CA5A P35218 2/20 0.42
CA7 P43166 2/20 0.42
CA5B Q9Y2D0 2/20 0.42
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
ATM Q13315 1/20 0.42
POLB P06746 1/20 0.40
HTT P42858 1/20 0.40
CA4 P22748 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
SLC6A4 P31645 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20653956 0.82 MEN1 (0.41) GAAPOLBHTTALDH1A1
SCHEMBL207236 0.82 CA2 (0.53) CA2CA1CA9CA12CA5A
SCHEMBL1807942 0.80 CA2 (0.47) CA2CA1CA9CA12CA5A
SCHEMBL12545632 0.79 GAA (0.57) GAACA2CA1CA9CA12
SCHEMBL1807944 0.79 CA2 (0.50) GAACA2CA1CA9CA12
SCHEMBL8215102 0.77 CA2 (0.55) CA2CA1CA9CA12CA5A
SCHEMBL1808966 0.77 CA2 (0.44) CA2CA1CA9CA12CA5A
SCHEMBL17088276 0.76 CA2 (0.43) CA2CA1CA9CA12CA5A
SCHEMBL4481727 0.76 CA2 (0.42) CA2CA1CA9CA12CA5A
SCHEMBL1808967 0.76 CA2 (0.53) CA2CA1CA9CA12CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0982286-A2 Diene compounds and process for preparing the same Takasago International Corporation (JP) 2000-03-01 EP disclosed