Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.52 |
| ▸ | F10 | P00742 | 12/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CALML3 | P27482 | 1/20 | 0.47 |
| ▸ | SDHA | P31040 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702035 | 1.00 | MAOA (0.52) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL7702033 | 0.93 | F10 (0.53) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL6397708 | 0.88 | F10 (0.52) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL6397715 | 0.88 | F10 (0.52) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL8163146 | 0.87 | MAOA (0.48) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL8169581 | 0.87 | MAOA (0.48) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL6963059 | 0.87 | MAOA (0.48) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL8163144 | 0.87 | MAOA (0.48) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL7710555 | 0.86 | MAOA (0.52) | MAOAF10MAOBLMNAPTGS1 | |
| SCHEMBL8169812 | 0.86 | MAOA (0.52) | MAOAF10MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083967-A | ANTIMICROBIAL AGENTS; ASSAY FOR DETERMINING THE INHIBITORY ACTIVITY OF OXAZOLIDINONES TO HUMAN MONOAMINE OXIDASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | claimed |
| US-6083967-A | ANTIMICROBIAL AGENTS; ASSAY FOR DETERMINING THE INHIBITORY ACTIVITY OF OXAZOLIDINONES TO HUMAN MONOAMINE OXIDASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | disclosed |